WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID. The second row lists the following statistics:
Finally, genes in the gene set are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:Transcription Target       Name:hsa_RYTTCCTG_V$ETS2_B       ID:DB_ID:2415
C=1074; O=11; E=1.47; R=7.49; rawP=2.04e-07; adjP=1.26e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000168067 NA MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 5871 ENSG00000168067
2  ENSG00000125878 NA TCF15 transcription factor 15 (basic helix-loop-helix) 6939 ENSG00000125878
3  ENSG00000167434 NA CA4 carbonic anhydrase IV 762 ENSG00000167434
4  ENSG00000135439 NA AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 116986 ENSG00000135439
5  ENSG00000131477 NA RAMP2 receptor (G protein-coupled) activity modifying protein 2 10266 ENSG00000131477
6  ENSG00000167996 NA FTH1 ferritin, heavy polypeptide 1 2495 ENSG00000167996
7  ENSG00000198844 NA ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 22899 ENSG00000198844
8  ENSG00000120279 NA MYCT1 myc target 1 80177 ENSG00000120279
9  ENSG00000130032 NA PRRG3 proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane) 79057 ENSG00000130032
10  ENSG00000074416 NA MGLL monoglyceride lipase 11343 ENSG00000074416
11  ENSG00000130307 NA USHBP1 Usher syndrome 1C binding protein 1 83878 ENSG00000130307


Database:Transcription Target       Name:hsa_CAGGTG_V$E12_Q6       ID:DB_ID:2409
C=2450; O=16; E=3.35; R=4.77; rawP=1.19e-07; adjP=1.26e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000168067 NA MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 5871 ENSG00000168067
2  ENSG00000174640 NA SLCO2A1 solute carrier organic anion transporter family, member 2A1 6578 ENSG00000174640
3  ENSG00000054179 NA ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 954 ENSG00000054179
4  ENSG00000129757 NA CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 1028 ENSG00000129757
5  ENSG00000204248 NA COL11A2 collagen, type XI, alpha 2 1302 ENSG00000204248
6  ENSG00000125878 NA TCF15 transcription factor 15 (basic helix-loop-helix) 6939 ENSG00000125878
7  ENSG00000007402 NA CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 9254 ENSG00000007402
8  ENSG00000240583 NA AQP1 aquaporin 1 (Colton blood group) 358 ENSG00000240583
9  ENSG00000130037 NA KCNA5 potassium voltage-gated channel, shaker-related subfamily, member 5 3741 ENSG00000130037
10  ENSG00000135439 NA AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 116986 ENSG00000135439
11  ENSG00000092421 NA SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 57556 ENSG00000092421
12  ENSG00000135502 NA SLC26A10 solute carrier family 26, member 10 65012 ENSG00000135502
13  ENSG00000121764 NA HCRTR1 hypocretin (orexin) receptor 1 3061 ENSG00000121764
14  ENSG00000129993 NA CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 863 ENSG00000129993
15  ENSG00000182132 NA KCNIP1 Kv channel interacting protein 1 30820 ENSG00000182132
16  ENSG00000186994 NA KANK3 KN motif and ankyrin repeat domains 3 256949 ENSG00000186994


Database:Transcription Target       Name:hsa_GGGAGGRR_V$MAZ_Q6       ID:DB_ID:2430
C=2250; O=12; E=3.08; R=3.90; rawP=4.48e-05; adjP=0.0019
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000121764 NA HCRTR1 hypocretin (orexin) receptor 1 3061 ENSG00000121764
2  ENSG00000174640 NA SLCO2A1 solute carrier organic anion transporter family, member 2A1 6578 ENSG00000174640
3  ENSG00000204248 NA COL11A2 collagen, type XI, alpha 2 1302 ENSG00000204248
4  ENSG00000129993 NA CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 863 ENSG00000129993
5  ENSG00000125878 NA TCF15 transcription factor 15 (basic helix-loop-helix) 6939 ENSG00000125878
6  ENSG00000240583 NA AQP1 aquaporin 1 (Colton blood group) 358 ENSG00000240583
7  ENSG00000166265 NA CYYR1 cysteine/tyrosine-rich 1 116159 ENSG00000166265
8  ENSG00000135439 NA AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 116986 ENSG00000135439
9  ENSG00000167996 NA FTH1 ferritin, heavy polypeptide 1 2495 ENSG00000167996
10  ENSG00000131477 NA RAMP2 receptor (G protein-coupled) activity modifying protein 2 10266 ENSG00000131477
11  ENSG00000130032 NA PRRG3 proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane) 79057 ENSG00000130032
12  ENSG00000186994 NA KANK3 KN motif and ankyrin repeat domains 3 256949 ENSG00000186994


Database:Transcription Target       Name:hsa_CTGCAGY_UNKNOWN       ID:DB_ID:2137
C=756; O=7; E=1.03; R=6.77; rawP=7.65e-05; adjP=0.0024
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000135502 NA SLC26A10 solute carrier family 26, member 10 65012 ENSG00000135502
2  ENSG00000174640 NA SLCO2A1 solute carrier organic anion transporter family, member 2A1 6578 ENSG00000174640
3  ENSG00000204248 NA COL11A2 collagen, type XI, alpha 2 1302 ENSG00000204248
4  ENSG00000129993 NA CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 863 ENSG00000129993
5  ENSG00000125878 NA TCF15 transcription factor 15 (basic helix-loop-helix) 6939 ENSG00000125878
6  ENSG00000092421 NA SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 57556 ENSG00000092421
7  ENSG00000182132 NA KCNIP1 Kv channel interacting protein 1 30820 ENSG00000182132


Database:Transcription Target       Name:hsa_V$VDR_Q3       ID:DB_ID:2102
C=218; O=4; E=0.30; R=13.41; rawP=0.0002; adjP=0.0050
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000135439 NA AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 116986 ENSG00000135439
2  ENSG00000198844 NA ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 22899 ENSG00000198844
3  ENSG00000135502 NA SLC26A10 solute carrier family 26, member 10 65012 ENSG00000135502
4  ENSG00000125878 NA TCF15 transcription factor 15 (basic helix-loop-helix) 6939 ENSG00000125878


Database:Transcription Target       Name:hsa_TATAAA_V$TATA_01       ID:DB_ID:2456
C=1276; O=8; E=1.75; R=4.58; rawP=0.0003; adjP=0.0062
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000166265 NA CYYR1 cysteine/tyrosine-rich 1 116159 ENSG00000166265
2  ENSG00000120279 NA MYCT1 myc target 1 80177 ENSG00000120279
3  ENSG00000174640 NA SLCO2A1 solute carrier organic anion transporter family, member 2A1 6578 ENSG00000174640
4  ENSG00000215788 NA TNFRSF25 tumor necrosis factor receptor superfamily, member 25 8718 ENSG00000215788
5  ENSG00000204248 NA COL11A2 collagen, type XI, alpha 2 1302 ENSG00000204248
6  ENSG00000159640 NA ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 1636 ENSG00000159640
7  ENSG00000167434 NA CA4 carbonic anhydrase IV 762 ENSG00000167434
8  ENSG00000240583 NA AQP1 aquaporin 1 (Colton blood group) 358 ENSG00000240583


Database:Transcription Target       Name:hsa_V$ETS1_B       ID:DB_ID:2057
C=255; O=4; E=0.35; R=11.47; rawP=0.0004; adjP=0.0071
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000135439 NA AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 116986 ENSG00000135439
2  ENSG00000168067 NA MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 5871 ENSG00000168067
3  ENSG00000143772 NA ITPKB inositol-trisphosphate 3-kinase B 3707 ENSG00000143772
4  ENSG00000129993 NA CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 863 ENSG00000129993


Database:Transcription Target       Name:hsa_RGAGGAARY_V$PU1_Q6       ID:DB_ID:2447
C=495; O=5; E=0.68; R=7.38; rawP=0.0006; adjP=0.0093
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000135439 NA AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 116986 ENSG00000135439
2  ENSG00000168067 NA MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 5871 ENSG00000168067
3  ENSG00000198844 NA ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 22899 ENSG00000198844
4  ENSG00000129993 NA CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 863 ENSG00000129993
5  ENSG00000167434 NA CA4 carbonic anhydrase IV 762 ENSG00000167434


Database:Transcription Target       Name:hsa_CTTTGT_V$LEF1_Q2       ID:DB_ID:2428
C=1939; O=9; E=2.65; R=3.39; rawP=0.0012; adjP=0.0165
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000129757 NA CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 1028 ENSG00000129757
2  ENSG00000125878 NA TCF15 transcription factor 15 (basic helix-loop-helix) 6939 ENSG00000125878
3  ENSG00000240583 NA AQP1 aquaporin 1 (Colton blood group) 358 ENSG00000240583
4  ENSG00000040608 NA RTN4R reticulon 4 receptor 65078 ENSG00000040608
5  ENSG00000136114 NA THSD1 thrombospondin, type I, domain containing 1 55901 ENSG00000136114
6  ENSG00000092421 NA SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 57556 ENSG00000092421
7  ENSG00000132622 NA HSPA12B heat shock 70kD protein 12B 116835 ENSG00000132622
8  ENSG00000164105 NA SAP30 Sin3A-associated protein, 30kDa 8819 ENSG00000164105
9  ENSG00000101331 NA C20orf160 chromosome 20 open reading frame 160 140706 ENSG00000101331


Database:Transcription Target       Name:hsa_V$MMEF2_Q6       ID:DB_ID:2073
C=268; O=3; E=0.37; R=8.18; rawP=0.0060; adjP=0.0349
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000198844 NA ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 22899 ENSG00000198844
2  ENSG00000174640 NA SLCO2A1 solute carrier organic anion transporter family, member 2A1 6578 ENSG00000174640
3  ENSG00000204248 NA COL11A2 collagen, type XI, alpha 2 1302 ENSG00000204248




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).